The process of egg donation is carried out in two phases. The first phase is known as ovarian hyperstimulation, where the donors receive a series of hormonal drugs that cause the ovaries to produce multiple mature eggs during one menstrual cycle. The most important step is to find a donor of the Intended parent's choice and intended parents can provide their choice after accessing the egg donor database (egg donor profiles).
Egg retrieval happens during the second phase. In this phase, the mature eggs are removed from the donor through a surgical procedure called transvaginal ultrasound aspiration. Throughout the procedure, the egg donors should spend around 60 hours for screening, testing, and medical appointments.
There are three classes of drugs that women generally receive during the ovarian hyperstimulation phase of donation. Several commercially available medications are available under these three classes:
- Gonadotropin-Releasing Hormone Agonist Analogues
- Follicle Stimulating Hormone (FSH) or Human Menopausal Gonadotropin (hMG)
- Human Chorionic Gonadotropin
The process of egg retrieval
Through transvaginal ultrasound aspiration, a tube is attached to an ultrasound probe, and a suctioning needle is passed into each ovary to remove mature oocytes from the follicles. To prevent nausea Oral promethazine(maybe) is used during the egg retrieval procedure. Post-procedure, 1-2 hours of stay is required for the donor in the clinic and then she can return to her home for further recovery. Then a follow-up exam and ultrasound one-week post-retrieval. Oral antibiotics such as doxycycline are prescribed to prevent infection.
How Egg Donation Works?
- We receive eggs from the donor with her consent and some legal formalities. This process will take 12-14 days after the menstruation/monthly period cycle.
How is egg donation program is applied?
There are two types of relationships between egg donors and recipients. In some cases, those who donate eggs(egg donors) and those get eggs (IntendedParents) do not know each other they do not know each other’s identity this is known as anonymous egg donation program and in some cases sometimes they know each other it is known as non-anonymous egg donation program. However, in egg donation, this practice generally mainly consists of people who do not know each other. ARTbaby offers both the options as per the client’s sand legal requirements.
As it is known, in the treatment of in vitro fertilization, a treatment that will provide multiple egg development known as ovarian stimulation is applied to the egg donor to retrieve eggs. In egg donation, this process is done only to the woman who provides the eggs to the Intended Parents. The egg recipient women are not treated for ovarian stimulation. Because the recipient's eggs are not used due to poor quality of eggs or depletion of ovarian reserve or due to some risks related to treatment or both the ovaries were removed or damaged in the past.
Here, the women who are eggs recipient are treated only for the preparation of the endometrial lining of the uterus for greater pregnancy chances. In the treatment applied, the treatment of the egg recipient and the egg donor women are performed simultaneously. The embryos obtained from the eggs fertilized by the sperm of the recipient male partner can be used fresh or can be used later by freezing. Freshly used embryos are subjected to a microinjection process called ICSI by taking the sperm of the recipient male partner on the day of collection of the eggs. In the ongoing further stages of IVF with egg donation, procedures are carried out just as in self eggs IVF treatment cycle.
Instructions for egg donor recipients
To continue with egg donation, contact the financial coordinator to take full responsibility. The client may request insurance coverage to reduce the burden of the financial burden before initiating the medical procedure.
Consult a medical professional to check all screening test reports to ensure the suitability of the process.
Contact the nursing coordinator to obtain and supply logistics to continue the process and meet the requirement for the egg from the donor to continue the procedure.
The doctor informs the IVF treatment protocol that patients will follow all necessary steps during the procedure.
Which tests are applied to couples for egg donation to be successful?
LH, FSH, E2, and prolactin hormones are analyzed.
A pelvic ultrasound, uterine film or HSG is performed.
Blood tests are performed for infectious diseases such as anti HCV, HBsAg, and HIV.
Blood group analyzes are made.
TSH, T3, T4 tests are done.
Complete blood count and fasting blood glucose tests are applied.
In determining the donor egg donor, the physical characteristics of the prospective mother are taken into consideration.
Can egg sharing control the efficiency of the egg donor?
The egg donor can dream of building his own family as well as helping other infertile couples or single parents who want to start their own family. The egg donation program can also help the egg donor control its fertility. Before starting the egg donation process, the egg donor needs to test for fertility, genetic screening, and fertility specialists. During these screening tests, the egg donor may be aware of their reproductive health as well as the ability to produce live eggs that can turn into embryos after fertilization with high-quality sperm.
- To produce healthy and maximum eggs Hormonal injections(FSH/HMG) are given to the egg donor from day 1 or 2 of menstruation. UltraSound reports are used to monitor the growth of donor eggs. And injections are stopped two days before the procedure when the egg sizes reach 17-18mm. Mature are retrieved under general anesthesia. This procedure takes almost 30 minutes and the donor can go home in 3-4 hours after pick up.
- The whole egg pickup procedure takes almost half a day and the donor will be free to do the normal activity from the next day of the egg retrieval procedure if she feels well and normal.